Celiac disease (celiac sprue) causes problems in your digestive system when you eat gluten, a protein found in wheat and other grains. It’s more serious than a normal food intolerance, though. Celiac disease causes your immune system to attack gluten in your small intestine. The attack damages your small intestine and stops it from working properly. Celiac disease is an inherited autoimmune disorder that causes a reaction in your body to the protein, gluten. Gluten in your digestive system triggers your immune system to produce antibodies against it. These antibodies damage the lining of your small intestine (the mucosa). Damage to the mucosa in your small intestine impairs its ability to absorb nutrients from your food, causing nutritional deficiencies.
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